Isolated Omphalocele means that is the only diagnosis your baby has and shows no genetic contribution.
Non Isolated Omphalocele means along with the organs in the sac your baby may have some genetic anomalies, or chromosomal anomalies.
- Some more common associated diagnoses are:
  - OEIS- also called Cloacal Exstrophy is very rare in which the large intestines are outside of the abdominal cavity but are connected on either side by the bladder causing an abnormal connection of bowel and bladder and has 4 distinct abnormalities.
    - Omphalocele
    - Exstrophy of cloaca
    - Imperforate Anus
    - Spinal Defects
  - BWS-(Beckwith-Wiedemann Syndrome) is a genetic condition that is commonly associated with Omphalocele and can be tested for during an amniocentesis. Some common characteristics of BWS are a larger tongue and higher weight, abdominal wall defects, and low blood sugar.
  - Pentalogy of Cantrell- contains 5 birth defects (but not always all 5) and does usually require surgeries to fix each defect. This condition is very rare and can be found on prenatal diagnosis.
    - Diaphragmatic- hole in the diaphragm
    - Sternal- indentation of the breastbone
    - Pericardial
    - Cardiac- septal defects or heart located outside of chest
    - Abdominal Wall- omphalocele
  - Heart anomalies
    - Septal defects (most frequent)
    - Tetralogy of Fallot
    - Ectopia Cordis
    - Tricuspid Atresia